No.14 May 2019

Tracing the way the information acts on the human psyche and physiology

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• Dear reader!

  The present issue of our journal is of very special nature. We are constantly analyzing not only the readers’ focus of interest to the publications in our journal, but we are also tracing how cardiometry as a new science is realized by medical doctors and how they apply it in their practice. Undoubtedly, the mathematical fundamentals of hemodynamics are very difficult to understand not only by doctors, but even by mathematicians. Therefore, we have decided to collect in the first section of the present issue all the basic, previously published, mathematical concepts of hemodynamics as a complete collection part, in order to provide our readers with a convenient reference form. We think that this is an absolutely reasonable idea, since our journal always offers a thematic outline philosophy. We can see that it plays an important role in attracting the readers’ attention all over the world.

• Report

  The G.Poyedintsev - O. Voronova mathematical model of hemodynamics

  Published with the support of RFBR (grant No. 18-29-02073)
  Olga K. Voronova, Mikhail Y. Rudenko, Vladimir A. Zernov

  The objective is to demonstrate the features of an original mathematical model of hemodynamics, developed by Russian researchers G.Poyedintsev and O.Voronova.

   Hemodynamics  Biophysics  Cardiocode  ECG  Human hemodynamics mathematical model by G Poyedintsev – O Voronova

• Report

  Motion of blood formed elements in a pulsatile hemodynamic flow

  Vladimir I. Timoshenko, Nikolay N. Chernov

  This paper offers some results obtained in our studies on the motion of individual formed elements in blood with due regard of a pulsatile flow of the plasma in the blood vessels. An analysis of the process of the motion of the blood particles having different shapes in a pressure wave variable field of the pressure wave has been completed herein.

   Blood formed elements  Motion  Pressure wave variable field  Human circulatory system  Physical models of motion of formed elements

• Original research

  The new analytical solution of the 3D Navier-Stokes equation for compressible medium clarifies the sixth Millennium Prize problem

  Sergey G. Chefranov   Artem S. Chefranov

  The limitations of capabilities of the existing mathematical weather prediction (including forecasting for weather-sensitive individuals) cannot be duly realized nowadays due to the fact that till now there is no proof of the existence and uniqueness of smooth solutions of the three-dimensional (3D) Navier-Stokes equation (in any finite period of time).

   Vortex flow  Turbulence  Viscosity  Compressibility  Hydrodynamics

• Report

  The ECG in a new capacity: the most informative source of data on aerobic and anaerobic processes in the cardiac muscle fiber tissue cells

  Published with the support of RFBR (grant No. 18-29-02073)
  Mikhail Y. Rudenko, Vladimir A. Zernov, Konstantin K. Mamberger, Sergey M. Rudenko, Dmitry F. Makedonsky

  The article is devoted to a novel noninvasive measurement of parameters of metabolic processes in the cardiac muscle fiber cells upon an original ECG processing. Theoretically substantiated is an original method of the ECG cardiac cycle phase analysis, which allows measuring the concentration of oxygen, lactate and phosphocreatine in arbitrary units in the cardiac muscle fiber cells in each cardiac cycle.

   Cardiometry  Cardiometric method  Cardiac muscle fiber tissue cell metabolism  Lactate  Phosphocreatine  Oxygen  Cardiac cycle phase analysis  ECG
• Visit by Vladimir Zernov and Mikhail Rudenko to the Institute of Cell Biophysics, RAS

  Our Editor-in-Chief and Deputy Editor have visited the Institute of Cell Biophysics at the Russian Academy of Sciences (Pushchino, Moscow Region) on the 27th of February 2019 in order to discuss some frontier research issues with Prof., M.D. Eugene I. Maevsky, who is the Head of the Lab for Biological System Energetics and the Research Director of the above RAS Institute. The 3-hour friendly discussion has been devoted to some significant results obtained upon completion of original scientific investigations focused on cell metabolism. It was enjoyable to remember the time of establishing and developing the Research Institute: this unique research institution has been a leader in fundamental biophysics research in the former Soviet Union, and the discoveries made by its researchers have made possible to identify and interpret the mechanisms responsible for energy transformation in a cell under different conditions found in a human organism.

• Review

  Justification for measurement equation: a fundamental issue in theoretical metrology

  Aleksandr V. Prokopov

  A review and a critical analysis of the specialized literature on justification for the measurement equation and an estimation of a methodical error (uncertainty) of the measurement result are presented in the paper, and some prospects for solving of the issue are discussed herein.

   Error  Uncertainty  Measurement equation (model equation)  Physical and mathematical model  Algorithm

• Lectures

  Cardiometry laws and axioms

  Axiomatics is method of science formation used in all natural science. The axiomatcs objective is to prove that the observed phenomenon represents the varity. Further on, the proved phenomenon is used in the function of the logical ratiocination for further conclusions.

• Original research

  Coincidence of renal artery stenosis and coronary artery stenosis

  Hossein Nough, Mohammad Reza Najarzadegan, Aryan Naghedi, Ali Reza Riazi1, Leila Hadiani, Seyede Mahdieh Namayandeh

  The aim of this study was to investigate the prevalence of renal artery stenosis in patients with severe coronary artery disease or stenosis of the left main coronary artery.

   Renal artery stenosis  Coronary artery stenosis  Hypertension  Coronary artery angiography  Renal angiography

• Original research

  The relationship between severity of coronary artery disease and mean platelet volume

  Hamidreza Varastehravan, Aryan Naghedi, Hossein Nough, Hamideh Pourmirafzali

  Increased MPV is a risk factor for cardiovascular diseases and can be associated with coronary artery involvement. In this study, we aimed to investigate the relationship between the severity of coronary artery disease and MPV.

   Mean platelet volume  SYNTAX score  Coronary artery  Risk factor

• Original research

  Prospects for the application of mathematical modeling in clinical medicine

  Oleg V. Gaisenok, Victor N. Lituev

  The aims of the study are to follow the correlation of СAD development with various clinical and laboratory parameters and risk factors in a cohort of patients with multiple medical conditions and evaluate the effect of various parameters in the development of the disease using a new mathematical model approach.

   CAD  Risk factors  Mathematical modeling  Triggers  Interaction graph  Aggregated matrix

• Original research

  Challenging task of identification of cardiac cycle tones: refined development of a PCG signal processing system

  Yeldos A. Altay, Artem S. Kremlev, Aygerim A. Sadykova

  This article presents some results of processing of phonocardiography signals (PCG signals) for cardiac cycle tone identification under ambient noise of varying intensity. For PCG signal processing, proposed is a refined approach based on active band pass filter bank, which allows improving an accuracy of cardiac cycle tone identification under ambient noise.

   Processing  Phonocardiogram  Filter bank  Identification  Cardiac cycle tones  Electronic stethoscope  Visualization  Heart biomechanics

• Original research

  Cardiometric detection of effects and patterns of emotional responses by a human individual to verbal, audial and visual stimuli

  Aleksandr S. Ognev, Vladimir А. Zernov, Elvira V. Likhacheva, Lyubov P. Nikolaeva, Mikhail Y. Rudenko, Diana D. Dymarchuk, Denis S. Yesenin, Polina А. Maslennikova, Nikita V. Mizin

  The article presents the results of an experimental study of the cardiometric detection of a person’s emotional reactions to verbal, audial and visual stimuli.

   Cardiometry  Cardiocode  Sthenic reaction  Asthenic reaction  Oculometric diagnostics  Eyetracker

• Original research

  Use of cardiometry and oculography in concealed information detection

  Aleksandr S. Ognev, Vladimir A. Zernov, Elvira V. Likhacheva, Lyubov P. Nikolaeva, Mikhail Y. Rudenko, Aleksey A. Tyrtyshny, Denis S. Yesenin, Polina A. Maslennikova, Nikita V. Mizin

  The article presents the results of an experimental study on the use of cardiometry and oculography to detect concealed information. It has been shown that a complex assessment of the person’s emotional-cognitive state based on cardiometric and oculographic recording of reactions to specially selected stimulus material of visual and audial modality can be successfully used in concealed information detection.

   Cardiometry  Cardiocode  Eyetracker  Lie detection  Psycho emotional reaction

• Original research

  Validity of cardiometric performance data: an integral part of complex assessment of training session effectiveness

  Aleksandr S. Ognev, Vladimir А. Zernov, Elvira V. Likhacheva, Lyubov P. Nikolaeva, Mikhail Y. Rudenko, Rosalina S. Kagonyan, Polina А. Kozintseva, Polina А. Maslennikova, Nikita V. Mizin

  The paper offers some results from our experimental studies to determine validity of a complex performance fingerprint: the Baevsky stress index used to assess effectiveness of training programs: training sessions targeted at formation of phsychosomatic self-regulation skills and visual & verbal practical training course aimed at development of emotional intelligence.

   Cardiometry  Cardiocode  Validity  Training  Training effectiveness

• Original research

  Cardiometric taxonomy of stress-inducing potential in diverse domestic situations

  Aleksandr S. Ognev, Vladimir А. Zernov, Elvira V. Likhacheva, Lyubov P. Nikolaeva, Mikhail Y. Rudenko, Diana D. Dymarchuk, Denis S. Yesenin, Polina А. Maslennikova, Nikita V. Mizin

  The aim of our study is to empirically verify the conceptual possibility of constructing a taxonomy of diverse domestic situations, which may become the basis for choosing the best ways to increase an individual stress resistance in a human subject.

   Cardiometric taxonomy  Cardiocode  Eyetracker  Stress resistance  Eustress  Distress  Domestic situations

• Analytical Note

  Cardio-oculometric (cardio-oculographic) detection of functional states in a human individual

  Aleksandr S. Ognev

  The cardio-oculometric detection (COD) is an integrated method aimed at studying personal preferences, individual traits and current functional states of a human individual. The method is based on the use of some cardiac markers and parameters of oculomotor activity in response to specially selected visual and audial stimuli.