The current issue of our journal has been published. Since the previous issue CARDIOMETRY has been making rapid strides. It is important to note that the journal’s papers have served not only the purpose of formulation of new scientific problems, but also the purpose of their solutions.

Problems of validation and verification are very critical in medicine. The absence of adequate models describing biophysical processes in the organism leads to using only practical evidence for these purposes that hinders innovations. But advances in medicine require new effective ways to solve these problems. Cardiometry as a new field in cardiology offers a new philosophy of validation and verification based on the classical proof theory borrowed from natural sciences. The aim hereof is to provide a new methodology for validation and verification for cardiovascular diagnostics.

A shortcoming common to all existing designs of mechanical cardiac valve prostheses is an increased trombogenicity caused, among other factors, by the lack of hydrodynamic compatibility between the luminal part of the prosthesis and the patterned blood flow. The aim of the study is to design and test our new mechanical aortic valve prosthesis to exclude life-long anticoagulation treatment.

The observed experimental and natural phenomenon of cyclone-anticyclone vortex asymmetry implies that a relatively more stable and showing a longer life, as well as a relatively more intense mode of rotation with an anticyclonic circulation direction (opposite to the direction of rotation of the medium as a whole) is realized as compared with an oppositely directed rotation of the cyclonic vortex mode. Until now, however, it was not a success to identify a universal triggering mechanism responsible for the formation of the corresponding breaking of chiral vortex symmetry.

Cardiac allograft vasculopathy (CAV) accounts for major morbidity and mortality late in the heart transplant (HTx) history. The role of antibodies (Abs) directed against human leukocyte antigens (HLA) and non-HLA antigens in the pathogenesis of CAV are still under investigation.

Arrhythmogenic right ventricular dysplasia is a rare entity and a significant cause of sudden death especially in the Italian population and athletes. The familial form is uncommon especially in the Afro-Caribbean population.

The phase characteristics of a rheogram are described in literature in general only. The existing theory of impedance rheography is based on an analysis of the form of rheogram envelopes, but not on the phase-related processes and their interpretation according to the applicable laws of physics.