No.12 May 2018

A shortcoming common to all existing designs of mechanical cardiac valve prostheses is an increased trombogenicity caused, among other factors,…

Attempts to create an artificial heart were highlighted by our journal one year ago. Now we can say that there…

The article presents the results of space experiment “Pneumocard”. The investigation involved all 25 Russian members of the ISS crew.…

This paper deals with solving of a century-old paradox of linear stability for the Hagen-Poiseuille flow. A new mechanism of…

No.12 May 2018

Biological rhythms: influence on the cardiovascular system performance

Needless to say, the idea of our Journal is to offer most exclusive research papers on problems associated with investigations of the human cardiovascular system. We are happy to state that the popularity of our Journal throughout in the world has been growing steadily. We believe the foundation for our success has been laid by the results achieved by our authors, and it is applicable both to theory and practice. The theories presented in the papers have valuable use and advantages in practical activities.

Offered is an overview of the author's papers in exploring an interface between biological rhythms of energy, function and biosynthesis in a nerve cell of a crayfish stretch receptor. Parameters of mitochondrion aggregation rhythms integrally determine the energy metabolism in the cell.

An overview of the author’s original works dedicated to the hierarchy of biological rhythms, chronodiagnostics and bio-controlled chronophysiotherapy is presented herein. Stability of biosystems is based on harmony of discrete spectra of their biological rhythms with a spectrum of normal cosmoheliogeophysical rhythms.

This paper develops three interconnected ideas about measurements of durations, of the calendar times and of the time in historical processes. It is shown that although we cannot predict ahead of time what exact novelties will arise in the noosphere, we are able to estimate a periodicity of the radical changes occurring in the cultural history.

Original Research

Mechanisms of the action of endogenous electrotonic influences and exogenous factors on biological rhythms of neurons

Valery I. Orlov, Aleksandr G. Sukhov, Oleg I. Kit, Alla I. Shikhlya­rova, Tatyana P. Protassova, Mikhail Y. Rudenko, Evgeniya Y. Kirichenko, Svetlana Y. Fillipova, Sergey G. Pashintsev

Subjects of our experimental studies were neurons in the snail Helix Pomatia, from which continuous intracellular recordings according to our specific microelectrode recording technique were produced.

In order to reveal the functional interrelationships of the main physiological characteristics of the organism with the external environment exogenous abiotic factors, as well as the evaluation of the magnetic field factor effect on the morphofunctional status main characteristics, 18 healthy men aged 25–49 years old, residents of the North-East of Russia (Magadan) were examined.

Technical report

The phonocardiographic data recording & processing system: an effective approach

Kulyash K. Makesheva, Eldos A. Altay, Aygerim A. Sadykova

Some results obtained in recording and processing of phonocardiograms are presented herein. To process phonocardiographic signals, a cascade filtration method has been used that allows detecting tones of the cardiovascular system in the background noise. The effectiveness of the proposed processing method is demonstrated by the results of visualization.

The proposed editorial article touches upon aspects of fundamental medicine associated with the discovery of systems of nonspecific adaptation reactions in the organism as a whole. It is shown that the key law of the organism's response to the actions of the external and internal environment consists in the dependence between the reaction quality and the quantity (measure, intensity) of an acting factor.

Review

Inseparable relationship between intellectual services and high-tech medical equipment

Sergey V. Astanin, Natalia K. Zhukovskaya, Marina A. Zharkova

The social problems in any country, related to public health and demography, induce developments and production of diagnostic and therapeutic medical equipment. Such equipment belongs to high-tech products and requires to be accompanied by intellectual services for a successful promotion of medical products on the market under modern competitive conditions.

UPCOMING ISSUE

Our book in WoS™ Core Collection

We are glad to inform you that the book "Theoretical principles of heart cycle phase analysis" written by researchers from Russian New University has been accepted and indexed in The Book Citation Index in Web of Science™ Core Collection

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