No.3 November 2013

The detected phenomena of shunting of blood from large arterial trunks into large venous vessels is considered herein. The Cardiocode…

This paper deals with a study of central hemodynamics in 363 pediatric patients with burn shock as compared with a…

In the suggested here linear theory of hydrodynamic instability of the Hagen - Poiseuille flow it is counted the possibility…

To overcome numerous contradictions in the knowledge of the blood transportation, a hypothesis was supposed asserting the swirling pattern of…

No.3 November 2013

Creation of artificial heart: engineering and ethical issues

The topics of the current issue cover creation of artificial heart: both engineering and ethics. Primarily it should be noted that our idea is to consider these problems not in the context of the latest technological advancements accompanied by a further definition of problems of this sort, but basically by shaping a discussion what research should be performed for this purpose at next stages.

To overcome numerous contradictions in the knowledge of the blood transportation, a hypothesis was supposed asserting the swirling pattern of blood flow in the heart and main vessels which resembles tornado-like flows and which is widespread in nature. These flows can be exhaustively described by the exact solutions of the nonstationary hydrodynamic Navier-Stokes equations and the continuity equations for the class of viscous swirling flows offered by Kiknadze - Krasnov.

Up to the present, ECGs have been classified on the basis of the analysis of the ECG curve shape. But this made impossible to classify many ECG shapes. The most promising methods for the classification must evaluate each of the 10 cardiac cycle phases both by their functions and hemodynamic parameters. The aim hereof is to develop the new classification principles for all possible ECG shape variations.

A cardiac muscle performance assessment in terms of acid-alkaline balance has never been carried out before. The studies show it is possible to evaluate indirectly aerobic, anaerobic and phosphocreatine processes in the cardiac muscle using ECG only. The aim is to study the capabilities of acid-alkaline balance measurement in the cardiac muscle using ECG only, in combination with the heart cycle phase analysis.

A review and a critical analysis of the specialized literature on justification for the measurement equation and an estimation of a methodical error (uncertainty) of the measurement result are presented in the paper, and some prospects for solving of the issue are discussed herein.

Leonardo da Vinci perhaps was the first who paid attention to the energetic efficiency of existence of vortices emerging near sines of Valsalva and defining normal functioning (opening) of aortal valve. However up to now a fundamental problem of defining of mechanisms of mysterious energetic efficiency of functioning of cardio-vascular system (CVS) of blood feeding of the organism is still remaining significantly not solved and this is, for example, one of the main restriction for the creation of artificial heart and corresponding valve systems.

Recipients of ventricular assist devices (VADR) have a higher incidence to develop antibodies (Abs) against human leukocyte antigens (HLA). Non-HLA antibodies like major histocompatibility complex class I-related chain A (MICA) and autoantibodies against angiotensin type 1 receptor (AT1R) and endothelin receptor A (ETAR) are also implicated in the pathogenesis of acute rejection and allograft vasculopathy. We monitored non-HLA- and HLA-Abs in VADR up to one year after implantation.

In the article main principles of ballistocardiography are considered. Special attention is paid to registration of the spatial ballistocardiogramm. There exist two principles of ballistocardiography: dynamic and seismic. In the event of dynamic ballistocardiography body displacements align to an extent with shifting of the general center of body gravity.

There are various indications for a mechanical circulatory support (MCS) devices implantation. We report a case of the use of the MCS in a 39 year old male with acute circulatory collapse and at immediate risk of death after endomyocardial biopsy in order to keep the patient alive until intrinsic cardiac function recovers sufficiently to remove the MCS.

The results of study of an artificial aortic valve by the heart cycle phase analysis are given in the paper. The main aim of the study is identifying the artificial aortic valve influence on cardiovascular system functions, the way and ranges of these functions change. The results of phase blood volume measurement and the numerical values that characterize the metabolic processes in heart muscles are given herein.

To overcome numerous contradictions in the knowledge of the blood transportation, a hypothesis was supposed asserting the swirling pattern of blood flow in the heart and main vessels which resembles tornado-like flows and which is widespread in nature. These flows can be exhaustively described by the exact solutions of the nonstationary hydrodynamic Navier-Stokes equations and the continuity equations for the class of viscous swirling flows offered by Kiknadze - Krasnov.

The "Science, technology, society and Nobel movement" International Nobel Congress (The Tenth International Meeting-Conference) for Nobel Prize Winners and Nobelists devoted to the 180th Anniversary of Alfred Nobel and the 25th Anniversary of the International Information Nobel Center (IINC) took place in Moscow and Tambov (Russia), on 28-31 October 2013.
Our scientific school “Research of cardiovascular system hemodynamics” has been working for more than 10 years at the Russian New University, Moscow, Russia (www.rosnou.ru). As a result, we have created CARDIOMETRY, a fundamentally new scientific field in cardiology.
The ESC 2013 annual congress took place in Amsterdam, the Netherlands. Our journal CARDIOMETRY was represented there for the first time. The journal attracted much attention. A lot of visitors enjoyed the chance to learn more about Cardiometry publications.
The Working Group welcomes suggestions for support and scientific endorsement of consensus documents, standardization reviews, focused seminars and meetings, and professional collaboration and exchange programmes.

UPCOMING ISSUE

Our book in WoS™ Core Collection

We are glad to inform you that the book "Theoretical principles of heart cycle phase analysis" written by researchers from Russian New University has been accepted and indexed in The Book Citation Index in Web of Science™ Core Collection

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