1 State Scientific Center of the Russian Federation, Institute of Biomedical Problems of the Russian Academy of Sciences, 123007, Russia, Moscow, 76A Khoroshevskoye Ch.
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The paper presents the results of the long-term medical & ecological investigations conducted during the experiment Mars-500. Methodology of conducting the long-term medical & ecological investigations and the applied methods are considered. The results are presented in the materials of the research conducted in Russian Federation and Republic of Belarus (Moscow, Syktyvkar, Yekaterinburg, Izhevsk, Magadan and Minsk). For comparative evaluation of the functional state of different reference groups the notion of ‚Äúecological stress‚ÄĚ was introduced. It depends upon the degree of dominance of the activity of the sympathetic member of the regulatory system over the parasympathetic member. Application of probabilistic approach to the assessment of the functional state and adaptation level with the FR (functional reserve) and the DT (the degree of tension) of the regulatory mechanisms proved the detected peculiarities of the heart rhythm vegetative regulation. Clear dependency of the functional state of the volunteers on geographic location of regions and climatic parameters is observed. Almost every HRV indicator is characterized by seasonal dynamics. Seasonal dynamics data is exemplified by the research conducted in Yekaterinburg and Syktyvkar. During the earth-bound experiment Mars-500 flight conditions to Mars were simulated. Results of the long-term medical & ecological investigations conducted simultaneously with the experiment Mars-500 showed that health changes in practically healthy people do not usually exceed the limits of the prenosological state.
Roman M. Baevsky, Azalia P. Berseneva, Irina N. Slepchenkova, Anna G. Chernikova. Assessment of adaptation reactions in the participants of the long-term medical & ecological investigations during the experiment Mars-500; Cardiometry; No.2; May 2013; p.74-87; DOI: 10.12710/cardiometry.2013.2.7487 Available from: http://www.cardiometry.net/issues/no2-may-2013/assessment-of-adaptation-reactions