Displaying articles by keyword AT1R

ISSN 2304-7232

Study of artificial aortic valve influence on hemodynamics by…

The results of study of an artificial aortic valve by the heart cycle phase analysis are given in the paper.…

Phase characteristics of rheograms. Original classification of phase-related changes…

The phase characteristics of a rheogram are described in literature in general only. The existing theory of impedance rheography is…

Efficacy of enhanced external counterpulsation: our experience

A shortcoming common to all existing designs of mechanical cardiac valve prostheses is an increased trombogenicity caused, among other factors,…

Application of principles of space medicine to health monitoring…

Monitoring the health of astronauts based on the assessment of the functional state of the body within the realms of…

Identification of non-HLA antibodies in ventricular assist device recipients

Published in No.3 November 2013

Recipients of ventricular assist devices (VADR) have a higher incidence to develop antibodies (Abs) against human leukocyte antigens (HLA). Non-HLA antibodies like major histocompatibility complex class I-related chain A (MICA) and autoantibodies against angiotensin type 1 receptor (AT1R) and endothelin receptor A (ETAR) are also implicated in the pathogenesis of acute rejection and allograft vasculopathy. We monitored non-HLA- and HLA-Abs in VADR up to one year after implantation.