Displaying articles by keyword AT1R

ISSN 2304-7232

The role of cardiac resynchronization therapy in permanent atrial…

The aim of this article is a comprehensive review of the publications during the last decade in order to evaluate…

General problems of metrology and indirect measuring in cardiology:…

This paper treats general problems of metrology and indirect measurement methods in cardiology. It is aimed at an identification of…

The effects of long-term microgravity on autonomic regulation of…

The article presents the results of space experiment “Pneumocard”. The investigation involved all 25 Russian members of the ISS crew.…

Activation therapy: theoretical and applied aspects

The paper presents a brief review on how some concepts on the organism general adaptational reactions developed, including their role…

Identification of non-HLA antibodies in ventricular assist device recipients

Published in No.3 November 2013

Recipients of ventricular assist devices (VADR) have a higher incidence to develop antibodies (Abs) against human leukocyte antigens (HLA). Non-HLA antibodies like major histocompatibility complex class I-related chain A (MICA) and autoantibodies against angiotensin type 1 receptor (AT1R) and endothelin receptor A (ETAR) are also implicated in the pathogenesis of acute rejection and allograft vasculopathy. We monitored non-HLA- and HLA-Abs in VADR up to one year after implantation.