Recipients of ventricular assist devices (VADR) have a higher incidence to develop antibodies (Abs) against human leukocyte antigens (HLA). Non-HLA…
The paper reveals logical relationships between events, facts and results of research studies and exemplary materials of practical applications of…
In order to evaluate the vegetative regulation of blood circulation and assess individual health risks under conditions of the 520…
When analyzing the articles submitted to our current issue, we involved into the preparation processing some relevant papers deserving special…
Identification of non-HLA antibodies in ventricular assist device recipients
Recipients of ventricular assist devices (VADR) have a higher incidence to develop antibodies (Abs) against human leukocyte antigens (HLA). Non-HLA antibodies like major histocompatibility complex class I-related chain A (MICA) and autoantibodies against angiotensin type 1 receptor (AT1R) and endothelin receptor A (ETAR) are also implicated in the pathogenesis of acute rejection and allograft vasculopathy. We monitored non-HLA- and HLA-Abs in VADR up to one year after implantation.
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