The article considers the development of the periodic table of ECG phase changes which should reflect the variety of the…
The article aims at describing the theoretical principles of cardiometry as a fundamentally new scientific field which enables the accurate…
Chronodiagnostical methods for evaluating reserve and unfavourable responses of human cardiac function and under prolonged stress load.
Description of rapid and slow ejection phases in the cardiac cycle.
Occurrence of HLA- and non-HLA antibodies after heart transplantation are associated with cardiac allograft vasculopathy
Cardiac allograft vasculopathy (CAV) accounts for major morbidity and mortality late in the heart transplant (HTx) history. The role of antibodies (Abs) directed against human leukocyte antigens (HLA) and non-HLA antigens in the pathogenesis of CAV are still under investigation.
Identification of non-HLA antibodies in ventricular assist device recipients
Recipients of ventricular assist devices (VADR) have a higher incidence to develop antibodies (Abs) against human leukocyte antigens (HLA). Non-HLA antibodies like major histocompatibility complex class I-related chain A (MICA) and autoantibodies against angiotensin type 1 receptor (AT1R) and endothelin receptor A (ETAR) are also implicated in the pathogenesis of acute rejection and allograft vasculopathy. We monitored non-HLA- and HLA-Abs in VADR up to one year after implantation.
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