The paper presents the results of the long-term medical & ecological investigations conducted during the experiment Mars-500. Methodology of conducting the long-term medical & ecological investigations and the applied methods are considered.
Experience of cosmonauts’ health monitoring shows that in the study of healthy subjects clinical approach to the evaluation of various medical and physiological data is almost less effective than the evaluation of organism adaptive abilities. The idea of prenosological diagnosis and the concept of adaptive risks develop in space medicine last years. These new space technologies are being actively tested in terrestrial studies in systems as "home medicine".
The present paper deals with prenosological diagnostics as methodology of an estimation of functional states of an organism. Highlighted is its first practical application in space medicine, at long influence of stressful factors, including such factor unusual to terrestrial organisms as weightlessness.
The world scientific literature is rich in sources considering pathological changes in the central nervous system (CNS) in case of tumor growth. The topical issue is the study of mechanisms providing a stable performance of the brain as the highest section of nervous system which largely predetermine the oncology patients life quality.
This article considers possibilities of achieving the most effective therapeutic effect of intermittent hypoxia training (IHT) by initiating an activation and training reaction.
The proposed editorial article touches upon aspects of fundamental medicine associated with the discovery of systems of nonspecific adaptation reactions in the organism as a whole. It is shown that the key law of the organism's response to the actions of the external and internal environment consists in the dependence between the reaction quality and the quantity (measure, intensity) of an acting factor.