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Original research

Detection mec A gene and Susceptibity some various antibiotic of Staphlococcus aureus

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Abstract

Through the study conducted in Najaf Governorate, bacterial samples were collected from different places. We notice during the study that the results were divided into two parts. The first was that the antibiotic Vancomycin had the highest rate of sensitivity to most of the bacterial samples, and this can be explained as follows. The bacterial isolates do not possess resistance genes or phenotypic factors that are highly effective against this antibiotic. Therefore, the effect of the antibiotic was significant on most of the bacterial isolates. At the same time, some bacterial isolates showed resistance to the antibiotic Vancomycin. This can be explained by the fact that these isolates possessed resistance genes or Phenotypic factors are resistant to this antibiotic, so resistance has been shown in some bacterial isolates. As for the second section, we note that the bacterial isolates had a very high rate of resistance to all other types of antibiotics. This can be explained by the fact that these bacterial isolates possessed resistance genes, virulence factors, or both, which made them significantly more resistant to this antibiotic... and through review. Based on other research at the level of Iraq, as well as other countries, we notice that Staphylococcus aureus bacteria is constantly evolving in resistance to antibiotics. We also note that the places where samples are collected have a role in resistance and sensitivity to antibiotics. PCR technique was used for the detection of mecA gene in S. aureus isolates and results showed that 45% of isolates were mecA positive, while 55% of the isolates were mecA negative.

Imprint

Ali Salam Ali Al-Karaawi, Hazim A. N. Alhadrawi. Detection mec A gene and Susceptibity some various antibiotic of Staphlococcus aureus . Cardiometry; Issue 30; February 2024; p.109-113; DOI: 10.18137/cardiometry.2024.30.109113; Available from: https://www.cardiometry.net/issues/no30-february-2024/detection-mec-A-gene-susceptibity

Keywords

PCR technique,  mecA gene,  S. aureus isolates
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