Part 2. Vegetative regulation of blood circulation in the Martian crew individuals in the Mars 500 project

When analyzing the articles submitted to our current issue, we involved into the preparation processing some relevant papers deserving special…

The results of study of an artificial aortic valve by the heart cycle phase analysis are given in the paper.…

Leonardo da Vinci perhaps was the first who paid attention to the energetic efficiency of existence of vortices emerging near…

In the suggested here linear theory of hydrodynamic instability of the Hagen - Poiseuille flow it is counted the possibility…


Issues of health evaluation during simulated space mission to Mars

Part 2. Vegetative regulation of blood circulation in the Martian crew individuals in the Mars 500 project

Evgenie Y. Bersenev1Vasily B. Rusanov1*Anna G. Chernikova 1

1 State Scientific Center of the Russian Federation, Institute of Biomedical Problems of the Russian Academy of Sciences, 123007, Russia, Moscow, 76A Khoroshevskoye Ch.

* Corresponding author:
   +7 (499) 193-62-44
  This email address is being protected from spambots. You need JavaScript enabled to view it.


In order to evaluate the vegetative regulation of blood circulation and assess individual health risks under conditions of the 520 day isolation, used was an analysis of the heart rate variability (HRV). The most significant changes in the HRV values against the background data were reported in the second half of the said experiment. At that time, the heart rate (HR) values showed some reductions, the standard deviation of normal-to-normal beats (SDNN) was increased, and the simultaneous activation of all regulation members (pNN50 – parasympathetic regulation, IC and VLF – the sympathetic and neurohumoral regulation) occurred. The period of “the Mars orbiting”, the time of the crew dividing and “the landing to Mars” featured the highest level of the tension of the regulatory systems and the significant increase in the health risks. An assessment of the functional state of the organism and the adaptation level according to the degree of the tension (DT) of the regulatory systems and their functional reserve (FR) made it possible not only to confirm the presence of the changes identified by the commonly used HRV, but to make them more apparent as well. An assessment of group risks of adaptation disorders at all stages of the experiment provided support that on the average the risk category did not exceed the safe levels, and the functional state of the crew individuals remained within the zone of the physiological norm. Reported were a minor reduction in the functional reserves and a minor increase in the degree of tension.


Evgenie Y. Bersenev, Vasily B. Rusanov, Anna G. Chernikova. Vegetative regulation of blood circulation in the Martian crew individuals in the Mars 500 project; Cardiometry; No.2; May 2013; p.62-73; DOI: 10.12710/cardiometry.2013.2.6273 Available from:



Our book in WoS™ Core Collection

We are glad to inform you that the book "Theoretical principles of heart cycle phase analysis" written by researchers from Russian New University has been accepted and indexed in The Book Citation Index in Web of Science™ Core Collection


Founders of a new fundamental science: Cardiometry


Russian New University

Your online partner for English language editing, proofreading, medical writing, formatting, design & development and publication support services

Online ECG / Telemetry Certification Course

Teach you everything you need to interpret arrhythmia and administer a 12-lead EKG

Cardiocode - unique diagnostics of the heart