Relation of antistress and geroprotective effects of deuterium depleted water in aging female rats

A shortcoming common to all existing designs of mechanical cardiac valve prostheses is an increased trombogenicity caused, among other factors,…

In order to evaluate the vegetative regulation of blood circulation and assess individual health risks under conditions of the 520…

Capabilities of the cardiometric diagnostics based on the heart cycle phase analysis for identifying the primary cause of a disease…

It is shown that initiated by action of molecular viscosity impulse flow, directed usually from the moving fluid to limiting…

Original research

Relation of antistress and geroprotective effects of deuterium depleted water in aging female rats

Oleg I. Kit1Alla I. Shikhliarova1Galina V. Zhukova1*Stepan S. Dzhimak2Mikhail G. Barishev2Tatiana A. Kurkina1Elena A. Shirnina1Tatiana P. Protasova1

1 Rostov Research Institute of Oncology
Russia, 344037, Rostov-on-Don, 14th line str. 63

1 Kuban State University
Russia, 350040, Krasnodar, Stavropolskaya str. 149

* Corresponding author:
  This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

The use of deuterium depleted water (DDW) in a dosing regimen of 25-30 ml per day for five weeks in aging female rats (20-22 months) contributed to the overall correction of age-related disorders of the adaptive status, estrous cycle regulation and nonspecific resistance, as well as the appearance of visually distinct signs of rejuvenation of the animals. The obtained results show the relation between the geroprotective effect of DDW and the development of the general nonspecific antistress adaptation reactions of calm and elevated activation that can serve as an experimental basis for the development of an effective method of geriatrics and prevention of cardiovascular diseases and degenerative processes in women in the peri- and postmenopausal period.

Imprint

Oleg I. Kit, Alla I. Shikhliarova, Galina V. Zhukova, Stepan S. Dzhimak, Mikhail G. Barishev, Tatiana A. Kurkina, Elena A. Shirnina, Tatiana P. Protasova. Relation of antistress and geroprotective effects of deuterium depleted water in aging female rats. Cardiometry; No.10; May 2017; p.35–42; DOI: 10.12710/cardiometry.2017.10.3542; Available online: http://www.cardiometry.net/issues/no10-may-2017/geroprotective-effects

Keywords

UPCOMING ISSUE

Our book in WoS™ Core Collection

We are glad to inform you that the book "Theoretical principles of heart cycle phase analysis" written by researchers from Russian New University has been accepted and indexed in The Book Citation Index in Web of Science™ Core Collection

VIDEO ABOUT CARDIOMETRY

Founders of a new fundamental science: Cardiometry

www.vzernov.com

www.mrudenko.com

www.ovoronova.com

OUR PARTNERS

Russian New University


Your online partner for English language editing, proofreading, medical writing, formatting, design & development and publication support services


Online ECG / Telemetry Certification Course

Teach you everything you need to interpret arrhythmia and administer a 12-lead EKG


Cardiocode - unique diagnostics of the heart