Effects produced by automated plasmapheresis on morphofunctional data on cardiovascular system performance in ischemic heart disease patients

Original research

Effects produced by automated plasmapheresis on morphofunctional data on cardiovascular system performance in ischemic heart disease patients

Yury E. Malchevsky1*Aligeidar A. Ragimov2

1 Federal Research Center "Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences", Research Institute for Medical Problems in the North (RIMPN)
Russia, 660036, Krasnoyarsk, ul. Akademgorodok, 50

2 I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Russia, 119435, Moscow, ul. Bolshaya Pirogovskaya, 2, str. 4

* Corresponding author:
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Abstract

We have performed the study of the effects made by the automated plasmapheresis application on ischemic heart disease clinical manifestations, echocardiographic indices and heart rate variability in patients with exertional angina III-IV functional class. It has been found that the applied plasmapheresis method is capable to reduce the severity of the disease clinical manifestations and improve the echocardiographic characteristics of the heart, in particular, reduce the level of end-diastolic volume, and increase ejection fraction. The clinical effect is already apparent at the early stages of the treatment and remains unchanged even after 6 months thereof. Also revealed has been the normalization of heart rate variability, indicating a decreased activity of the sympathetic nervous system. It is concluded that the plasmapheresis method can be successfully used in practice by a wide range of hospitals, where patients with ischemic heart disease are monitored, including the ambulatory conditions.

Imprint

Yury E. Malchevsky, Aligeidar A. Ragimov. Effects produced by automated plasmapheresis on morphofunctional data on cardiovascular system performance in ischemic heart disease patients. Cardiometry; Issue 16; May 2020; р.117-122; DOI: 10.12710/cardiometry.2020.16.117122; Available from: http://www.cardiometry.net/issues/no16-may-2020/complex-treatment-of-chronic-heart-failure

Keywords

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