The paper reveals logical relationships between events, facts and results of research studies and exemplary materials of practical applications of the adaptational reactions. It is demonstrated that the stress reaction by H. Selye and the anti-stressor type adaptational reactions by L. Kh. Garkavi, E.B. Kvakina and M.A. Ukolova have become the cornerstone in development of scientifically grounded approaches to control of the organism states.
The paper presents a brief review on how some concepts on the organism general adaptational reactions developed, including their role in increasing the unspecific resistance in the organism. Demonstrated is periodicity of the patterns of anti-stressor type reactions (training, calm and elevated activation) and stress in a wide range of stimulation values.
The activity of key ferments in the Krebs cycle (SDH) and glycolysis (α-GPDH) in peripheral blood lymphocytes in animals and humans with cancer pathology is considered herein. Identified is a close relationship between the fermentative activity and non-specific integral reactions of an organism, the type of which can be regulated by factors of electromagnetic nature. Monitoring of signal energetic and adaptive reactions permits to adequately evaluate an efficacy of treatment and predict recovery.
The use of deuterium depleted water (DDW) in a dosing regimen of 25-30 ml per day for five weeks in aging female rats (20-22 months) contributed to the overall correction of age-related disorders of the adaptive status, estrous cycle regulation and nonspecific resistance, as well as the appearance of visually distinct signs of rejuvenation of the animals.