Jens Garbade

There are various indications for a mechanical circulatory support (MCS) devices implantation. We report a case of the use of…

Criteria of identification of individual heart cycle phases according to an ECG curve are described in this paper.

A review and a critical analysis of the specialized literature on justification for the measurement equation and an estimation of…

The article aims at describing the theoretical principles of cardiometry as a fundamentally new scientific field which enables the accurate…

Jens Garbade

Recipients of ventricular assist devices (VADR) have a higher incidence to develop antibodies (Abs) against human leukocyte antigens (HLA). Non-HLA antibodies like major histocompatibility complex class I-related chain A (MICA) and autoantibodies against angiotensin type 1 receptor (AT1R) and endothelin receptor A (ETAR) are also implicated in the pathogenesis of acute rejection and allograft vasculopathy. We monitored non-HLA- and HLA-Abs in VADR up to one year after implantation.

Cardiac allograft vasculopathy (CAV) accounts for major morbidity and mortality late in the heart transplant (HTx) history. The role of antibodies (Abs) directed against human leukocyte antigens (HLA) and non-HLA antigens in the pathogenesis of CAV are still under investigation.

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